Dr. Rhonda Patrick. Below summarizes the details: VSL #3 was originally created by Professor Claudio De Simone, and produced by VSL Inc. All the clinical studies before 2016 were performed on the original formula of VSL#3. I'm not saying that vitamin D is going to prevent you from getting covid-19 or it's a treatment, although I am involved in a clinical study where we're going to be testing a very small open arm study we can talk about. In 2014, she published a paper in the FASEB Journal on how vitamin D regulates serotonin synthesis & how it relates to autism. Its worth clarifying which fish oil supplements Rhonda isnt taking anymore for avoidance of confusion. Now, on to our guest My guest this episode is Rhonda Perciavalle Patrick, Ph.D., who works with Dr. Bruce Ames, the 23rd most-cited scientist across ALL fields between 1973 and 1984 (! If instead you view via a web browser, then the comment isnt at the top, and it may be hard to locate. Rhondas Method for Choosing Supplement Brands, Associations of dietary calcium intake and calcium supplementation with myocardial infarction and stroke risk and overall cardiovascular mortality in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition study (EPIC-Heidelberg), Calcium Intake From Diet and Supplements and the Risk of Coronary Artery Calcification and its Progression Among Older Adults: 10Year Followup of the MultiEthnic Study of Atherosclerosis (MESA), Omega-3: A Link between Global Climate Change and Human Health, Blood docosahexaenoic acid and eicosapentaenoic acid in vegans: Associations with age and gender and effects of an algal-derived omega-3 fatty acid supplement, Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies, The Omega-3 Index: Clinical Utility for Therapeutic Intervention, Vitamin D: A Micronutrient Regulating Genes, Vegetables and Mixed Dishes Are Top Contributors to Phylloquinone Intake in US Adults: Data from the 2011-2012 NHANES, Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease, The relationship between vitamin K and peripheral arterial disease, Lutein and Zeaxanthin and Their Roles in Age-Related Macular Degeneration, Lutein and Zeaxanthin Supplementation and Association With Visual Function in Age-Related Macular Degeneration, Dietary guidance for lutein: consideration for intake recommendations is scientifically supported, Zeaxanthin: Review of Toxicological Data and Acceptable Daily Intake, Increased Bioavailability of Ubiquinol Compared to Ubiquinone, Dark Chocolate Acutely Improves Walking Autonomy in Patients With Peripheral Artery Disease, Dark chocolate supplementation reduces the oxygen cost of moderate intensity cycling, Cocoa consumption dose-dependently improves flow-mediated dilation and arterial stiffness decreasing blood pressure in healthy individuals, The effect of flavanol-rich cocoa on the fMRI response to a cognitive task in healthy young people, Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa, Cognition, and Aging (CoCoA) study, Cocoa Flavanol Supplementation Influences Skin Conditions of Photo-Aged Women: A 24-Week Double-Blind, Randomized, Controlled Trial, Cadmium and lead in cocoa powder and chocolate products in the US Market, Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Studya randomized controlled trial, Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults. It also includes a section for brands specific to UK & Canada. The NHANES 2011-2012 study found only 57% of men and 37.5% of women (N = 4,306) met the adequate intake of K111Vegetables and Mixed Dishes Are Top Contributors to Phylloquinone Intake in US Adults: Data from the 2011-2012 NHANES Harshman et al. Lutein specifically is also found in egg yolks and animal fats. When asked what type of resveratrol she would take, she said a micronized powder form, and that a company called RevGenetics make that (noting again that she has no connection with them or any other supplement company). Of course, its worth noting that the amount of cocoa in regular chocolate is low so you want to be consuming high cacao content products to receive these benefits. There are over 40 (!) Joe Rogan, with his go-to fermented and sweetened/flavored tea called kombucha by GT's Kombucha for total gut health on the road. The supplement she uses, Pure Encapsulations Calcium K/D, has 200 mg of calcium per pill, which is what she takes daily. The curcumin group had a 28% improvement in their memory/attention abilities and fewer amyloid plaques and tau tangles in the brain, compared to the placebo. (2017). So where does the vitamin K2 supplementation come in? Its a higher dose per serving (750mg vs 500mg), which is based off clinical studies26Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Studya randomized controlled trial Mastroiacovo et al. Rhonda currently takes an omega-3 supplement called Norwegian PURE-3, which is touted as a high quality fish oil with low levels of oxidation. Her response in her May 2022 Q&A was that Athletic Greens contains a blue green micro algae called spirulina, which is a potential source of a liver toxin called microcistins. Dr. Rhonda Patrick has been making waves in the field of healthy aging. The supplement industry, surprisingly, is largely unregulated. (2008)36Probiotics: progress toward novel therapies for intestinal diseases Yan et al. Rogan was wowed by the evidence Patrick offered, suggesting that vitamin D status has a profound impact on COVID-19 outcomes. We've complied her top 11 supplement recommendations all in 1 place. Dr. Patrick's Daily Supplements Recommendations. For Zeaxanthin, according to this paper17Zeaxanthin: Review of Toxicological Data and Acceptable Daily Intake James Edwards | 2016 | Journal of Ophthalmology, the EU put an upper use level of 2 mg / day. Rhonda currently supplements vitamin K on the basis that its an insurance policy, in case she doesnt get enough K from vegetables. Interestingly, at price per gram of flavanols, it also works out cheaper than the original version ($2.22/gram vs $3.00/gram). She also questions the value of metformin in healthy individuals who exercise. In Rhondas June 2021 Q&A she mentions using collagen powder daily to benefit her skin, hair and joints. Below, vitamin D expert, Rhonda Patrick, Ph.D., shares the latest research on . All lists below are great to strengthen your immune function: Multivitamin - Pure Encapsulations O.N.E: One capsule daily (.) In part, this is because fish dont actually produce omega-3s, instead they get them from the plankton and algae in their diet so by consuming algae youre going direct to the source3Omega-3: A Link between Global Climate Change and Human Health Jing X. Kang | 2011 | Biotechnology Advances. Heart rate variability improves, blood pressure goes down, cardiovascular health improves, all-cause mortality decreases. One study in the Philippines found that for every standard deviation increase in vitamin D levels, people were 8x less likely to have a severe form of COVID-19 and 20x less likely to have a critical form of COVID-19. She says her interest in resveratrol stems mainly from preliminary clinical trials showing positive benefits in cognition for older and cognitively impaired adults, including: Her current reservation is around a study that showed 250mg/day of resveratrol blunted the positive effects of exercise42Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men Gliemann et al (2013). "I think vitamin D really is the star potentially."- stated on Joe Rogan before millions, May 2020 Dr. Rhonda Patrick Goes In Depth on the Benefits of Vitamin D 2,659,516 views May 14, 2020 Rhondas early mentor, Bruce Ames, researched what happens when our bodies have insufficient levels of micronutrients, and found that our bodies prioritize the scarce nutrients for functions related to survival and reproduction. She opts for the salmon roe rather than supplements, as its a potent, fresh source of phospholipids (~438 mg of EPA and ~514 mg of DHA per ounce). Namely: So when it comes to healthy individuals who exercise, she doesnt see any synergy with the use of metformin for improving healthspan and lifespan. This episode of The Tim Ferriss Show is sponsored by Bluehost, which I used for my first WordPress blog, and I still use them for sites today. However whilst pregnant, Rhonda stopped taking any non-essential supplements (including Nicotinamide Riboside) that could pose even the slightest risk to her child. ---Medical DisclaimerAffiliate DisclosurePrivacy Policy. Instead, consider: omega-3, glutamine, magnesium, calcium (if concerned about bone injury), vitamin D, and tart cherry juice for persistent soreness Introduction Dr. Andy Galpin ( @DrAndyGalpin ), Professor of Kinesiology at California State University, Fullerton, and one of the foremost experts in the world on the science and application of . Thorne Research D (Vitamin D3) Dr. Rhonda is also a huge advocate for vitamin D namely vitamin D3, the same kind one gets from the sun. Rhondas Pregnancy, Breastfeeding & Toddler Supplements. While Joe Rogan's TV presence has changed over the years, The Joe Rogan Experience podcast is one of his most successful projects. The aspect of melatonin production decreasing with age is important (see this study for more discussion). The goal of this blog is to share information around health and longevity, with the hope that others find it useful. Therefore its important to use blood testing to ensure youre staying within the healthy range. Close. (2010). Dr. Rhonda also supplements vitamin D (because she does not get enough sunlight), fish oil, magnesium, potassium, calcium, zinc, iodine, curcumin (a natural anti-inflammatory), and the . However, for example with her mother, who doesnt eat as many green vegetables, she encourages a larger supplemental dose. That said, its still relatively under studied compared to other supplements. A study, 200mg/daily resveratrol supplementation improved healthy 50-75 year olds memory recall, In another study, patients with alzheimers disease who took resveratrol saw improvements in cognition, and decreases in biomarkers of Alzheimers disease and inflammation, Reduction in gaining lean muscle mass whilst on an exercise program, compared to placebo, Inhibition of mitochondrial adaptations and improvements in cardiorespiratory fitness by 50 percent and diminished whole-body insulin sensitivity after aerobic exercise, Notes on many of the key things Rhonda has discussed about, Notes on the supplements Rhonda is giving to her, now, toddler (. In a non supplemented vegetarian/vegan diet, the primary source of omega-3 fatty acids comes from alpha linolenic acid (ALA), which is found in various plants (particularly flaxseed). (2016). So far weve discussed Rhondas morning supplements. 23andMes more expensive health package should include ApeE4 testing as standard. Note: since having her son she has less time for growing broccoli sprouts. It comes in 2 different forms, vitamin K1 (phylloquinone) and K2 (menaquinone). The link between Covid and Vitamin D deficiency hasn't been studied, but Dr. Patrick has theorizing that due to Covid entering from the ace2 receptor and Vitamin D deficiency has been shown to lead to problems with the ace2 receptors functioning. Rhonda pointed to a possible link between low vitamin D levels, and increased severity of Covid-19 disease. "This episode of the podcast is [] Rhonda has had David Sinclair on the podcast discussing the positive effects of Resveratrol. Smoothies are great because they are easy to make, quick to consume and are packed with nutrients. It is noticeably expensive, even for ubiquinol. Glucosamine and Chondroitin - 365's Glucosamine Chondroitin & MSM. See Rhondas Instagram post on collagen for more info. Fish oil is a supplement Rogan has mentioned he takes daily. A retrospective study in the Philippines found that for each standard deviation increase in serum vitamin D people were 7.94 times more likely to have a mild rather than severe COVID-19 outcome and were 19.61 times more likely to have a mild rather than critical outcome. Noting it also doubles as a (weak) alternative to painkillers. Especially when compared to the stringent regulations that are imposed on the pharmaceutical industry. In recent years its become popular amongst biohackers looking to extend their healthspan + lifespan. She has done extensive research on aging . This can be made by: In terms of which Moringa to use, Jeds studies used Kuli Kuli Moringa. Meet Dr. Rhonda Patrick Dr. Rhonda Patrick has a gift for translating complex scientific topics into actionable insights in her videos, podcasts, and articles. Fortunately it doesnt require much blood, just single drop onto a piece of card, which you then post back. Thorne Research (Vitamin D/K2) Another Thorne Research product that Dr. Rhonda Patrick includes in her daily supplements is the Thorne Research Vitamin D/K2. Moringa is derived from the leaves of the Drumstick Tree, which are harvested, dried and then powdered. You can instead skip to the next section Rhondas Method for Choosing Supplement Brands. If she misses a dose in the morning then she will typically double up in the evening. But more vitamin D isn't always better. Transcript and discussion of #1474 - Dr. Rhonda Patrick from The Joe Rogan Experience podcast. Combien gagne t il d argent ? 1. The average person loses ~0.5 kg of fluid from sweat in a typical 20-minute sauna session (average temp. We produce melatonin as the sun sets and night sets in, and we reduce production as the sun rises and our body preps for wakefulness. Whilst vitamin K1 is prioritized for use in the liver, vitamin K2 appears to be prioritized for use in the periphery, which will support calcium transport13The relationship between vitamin K and peripheral arterial disease Vissers et al. Get the full details of Dr Rhonda Patrick's supplement brands. Unfortunately, many people are low in vitamin K1, and therefore may have inadequate levels of K1 to support adequate calcium transport. However, the omega-3s EPA & DHA are also important to humans, so relying on ALA solely has a few issues: The good news is that research shows algae based omega-3s will raise EPA & DHA levels in vegans, even at relatively low dose7Blood docosahexaenoic acid and eicosapentaenoic acid in vegans: Associations with age and gender and effects of an algal-derived omega-3 fatty acid supplement Sarter et al. | 2022 | Nutrients15Lutein and Zeaxanthin Supplementation and Association With Visual Function in Age-Related Macular Degeneration Liu et al. Approximately 1/2 the US population are thought to be deficient in magnesium28Suboptimal magnesium status in the United States: are the health consequences underestimated? For example, as an Amazon Associate, I earn from qualifying purchases. Therefore she suggested to the subscriber to contact Althetic Greens for their microcystin testing data. (2014). It may have seemed unusual for him to speak of sensory deprivation tanks in such a way, but it was no the last word - he semiregularly . Below is a list of fish oils that have both low oxidation and heavy metal levels, as measured by the IFOS testing. Theyre particularly of interest in eye health, because theyre found in the eye lens and macular region of the retina. Vitamin K2 - Thorne Research K2/D3 Drops: One drop every two to three days. See Rhondas research section on metformin for more info. (2014) that showed this dose improves word recall and led to faster spatial memory versus the placebo. She goes on to say that in this Consumer Lab report, the CocoaVia brand was shown to have almost undetectable levels of cadmium and lead making it a safe option, and a key reason she opted for it. ncbi.nlm.nih.gov. Rhonda added Moringa powder to her diet after research from Jed Fahey at Johns Hopkins University. The results in men varied depending on age and weight. However, she was asked by a subscriber of hers what she thinks of it. So, if you see leafy green vegetables, you know youll be able to get some of the bound-up magnesium from it. Its estimated that around 25% of the population have at least 1 ApoE4 allele. (2017). Rhondas current hypothesis for why is that at lower doses resveratrol may act as a mild antioxidant, which then blunts the positive effects of exercise (similar to high dose Vitamin E). She also has a Bachelor of Science degree in biochemistry/chemistry from the University of California, San Diego. For example, probiotics can help regulate the innate and adaptive immune responses by modulating the functions of dendritic cells, macrophages, and T and B lymphocytes35Mechanisms of probiotic action: Implications for therapeutic applications in inflammatory bowel diseases Vanderpool et al. In the mornings she limits herself to just 1 coffee, to which she sometimes adds the Lairds mushroom blend mentioned above. Omega-3 Phospholipids, Alzheimers & APOE4. Her typical dose of vitamin D3 is 4,000iu, which is about in line with what Joe Rogan takes. The reason for this is that phospholipid DHA gets converted to DHA-lysoPC, by a specialized transporter called MFSD2A39Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid Nguyen et al (2014).
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